Details of Publication 648 for Project A240B:

Joham A, Ranasinha S, Zoungas S, Moran L & Teede H. Gestational Diabetes and Type 2 Diabetes in Reproductive-Aged women with Polycystic Ovary Syndrome. Journal of Clinical Endocrinology and Metabolism, 2014; 99(3): E447-E452

Context: Polycystic ovary syndrome (PCOS) affects 6–21% of women. PCOS has been associated with an increased risk of dysglycaemia including gestational diabetes (GDM) and type 2 diabetes (T2DM).Objective: To assess the prevalence of dysglycaemia and the impact of obesity in young reproductive-aged women with and without PCOS in a community-based cohort.Design: Cross-sectional analysis of data from a large longitudinal study (the Australian Longitudinal Study on Women’s Health (ALSWH)).Setting: General communityParticipants: Women were randomly selected from the national health insurance database. Standardised data collection occurred at 5 survey time points (years 1996, 2000, 2003, 2006 and 2009). Data from survey 4 (2006, n=9145, 62% of original cohort aged 18 to 23 years) were examined for this study.Main outcome measures: Self-reported PCOS, GDM and T2DMResults: In women aged 28 to 33 years, PCOS prevalence was 5.8% (95% CI: 5.3%-6.4%). The prevalence of GDM (in women reporting prior pregnancy) and T2DM was 11.2% and 5.1% in women with PCOS and 3.8% and 0.3% in women without PCOS respectively (p for both<0.001). PCOS was associated with increased odds of GDM and T2DM. After adjusting for age, Body Mass Index (BMI), hypertension, smoking and demographic factors, the odds of GDM (OR 2.1, 95% CI 1.1-3.9, p=0.02) and T2DM (OR 8.8, 95% CI 3.9-20.1, p<0.001) remained increased in women reporting PCOS.Conclusions: In a large community-based cohort of reproductive-aged women, PCOS was independently associated with higher risk of GDM and T2DM, independent of BMI. Aggressive screening, prevention and management of dysglycaemia is clearly warranted in women with PCOS.

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Details of Publication 648 for Project A240B:

Joham A, Ranasinha S, Zoungas S, Moran L & Teede H. Gestational Diabetes and Type 2 Diabetes in Reproductive-Aged women with Polycystic Ovary Syndrome. Journal of Clinical Endocrinology and Metabolism, 2014; 99(3): E447-E452

Context: Polycystic ovary syndrome (PCOS) affects 6–21% of women. PCOS has been associated with an increased risk of dysglycaemia including gestational diabetes (GDM) and type 2 diabetes (T2DM).Objective: To assess the prevalence of dysglycaemia and the impact of obesity in young reproductive-aged women with and without PCOS in a community-based cohort.Design: Cross-sectional analysis of data from a large longitudinal study (the Australian Longitudinal Study on Women’s Health (ALSWH)).Setting: General communityParticipants: Women were randomly selected from the national health insurance database. Standardised data collection occurred at 5 survey time points (years 1996, 2000, 2003, 2006 and 2009). Data from survey 4 (2006, n=9145, 62% of original cohort aged 18 to 23 years) were examined for this study.Main outcome measures: Self-reported PCOS, GDM and T2DMResults: In women aged 28 to 33 years, PCOS prevalence was 5.8% (95% CI: 5.3%-6.4%). The prevalence of GDM (in women reporting prior pregnancy) and T2DM was 11.2% and 5.1% in women with PCOS and 3.8% and 0.3% in women without PCOS respectively (p for both<0.001). PCOS was associated with increased odds of GDM and T2DM. After adjusting for age, Body Mass Index (BMI), hypertension, smoking and demographic factors, the odds of GDM (OR 2.1, 95% CI 1.1-3.9, p=0.02) and T2DM (OR 8.8, 95% CI 3.9-20.1, p<0.001) remained increased in women reporting PCOS.Conclusions: In a large community-based cohort of reproductive-aged women, PCOS was independently associated with higher risk of GDM and T2DM, independent of BMI. Aggressive screening, prevention and management of dysglycaemia is clearly warranted in women with PCOS.

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Substudies and Analyses

Substudies

Many participants have been invited to help by answering additional surveys outside of the major three yearly surveys. "Substudies" is the term used to describe these additional surveys and we thank everyone who has so willingly taken part in these. These surveys target particular areas of health, and have covered a wide range of topics including sleeping difficulties and disturbances, domestic violence, menopausal problems, urinary incontinence, leisure and time, diabetes and the future plans of younger women. 

Below are the titles of the substudies conducted by the Australian Longitudinal Study on Women’s Health.

2012

  • Vasomotor menopausal symptoms and risk of cardiovascular disease
  • Women's perceptions of information they received about alcohol use during pregnancy
  • Pilot survey of a random sample of the 1973-78 cohort to assess their attitudes to, and support for, recruitment of their children to a Next generation study (G2).

2011

  • Pilot survey of a random sample of the 1946-51 cohort to assess their attitudes to, and support for, recruitment of a male cohort.
  • An interdisciplinary investigation into the experience and impacts of living with drought for 3 generations of Australian women
  • Arthritis and women at midlife: The lived psychosocial experience

2010

  • Navigating back pain care: A sociological study of women's illness pathways within and between intersecting social worlds
  • Older women's interest in arts and crafts
  • Perinatal mental health: Psychosocial assessment, service utilisation and maternal and infant outcomes

2009

  • Experiences of motherhood.
  • The use of complementary and alternative medicines in older urban and rural women
  • Tracking the impact of drug regulatory actions
  • Depression and cardiovascular disease in a cohort of mid-aged Australian women
  • Complementary and alternative medicine use among mid age women
  • The predictors, antecedents and efficacy of treatment of postnatal depression in Australian women

2008

  • Men, Women and Ageing.

2007

  • Service utilisation and caregiving among mid-aged women.
  • Sleeping difficulty and sleeping medication use among older women.

2006

  • Work and retirement experiences among mid-aged women.
  • Validation of survey measures among older women.

2005

  • Work-life tensions: time pressure, leisure and wellbeing among dual earner parents.
  • Validity of self-reported height, weight and physical activity among mid-aged Australian women and men.
  • Older motherhood; young women's plans and views.

2004

  • Work-life tensions: time pressure, leisure and wellbeing among dual earner parents.
  • Family caregivers: do health and community services meet their needs?
  • Are cardiac conditions in older women managed appropriately?
  • A functional model of falls risk. HomeFAST Self Report Survey and HomeFAST Scoring are both available as pdfs.
  • Coping: the strategies used by young women coping with depressed mood.

2003

  • Baby boomers consider retirement: the ageing process from a generational perspective.
  • Pregnancy and contraception history.

2002

  • Contraception and young women.
  • Childlessness and factors associated with it among The Australian Longitudinal Study on Women’s Health participants.
  • Pregnancy risk taking in young Australian women.
  • Young women, multiple roles and mental health.
  • Determinants of weight maintenance in young women over time.
  • Stages of life and smoking behaviour among young women.
  • An exploration of the link between intimate partner violence, self esteem, body image, and use of cosmetic surgery.

2001

  • An examination into the aspirations of a group of young. Australian women in relation to work, education, relationships and children.
  • Mid-age women’s experience of relationship abuse.
  • Quality and accessibility of health care for women in Australia with diabetes.

2000

  • Menopausal women and heart disease. 
  • Women with menstrual symptoms, treatments tried, hysterectomy and satisfaction with outcomes.
  • Women and leisure beyond 2000: Patterns, perceptions, gender relations and well-being.

1999

  • What factors influence weight change at menopause?
  • Incontinence in Australian women: following up participants in the Australian Longitudinal Study on Women’s Health.
  • Violence and Abuse: an assessment of mid-aged women’s experiences.
  • Young women, class and neighbourhood.
  • Use of health care services by elderly women with complex health needs.
  • Health care seeking and health care experiences in rural and metropolitan New South Wales.
  • Alcohol consumption in Australian women.
  • Women and leisure towards 2000: Does all work and no play make Jill unwell.

1998

  • Physical activity in older people.
  • Dieting women: pressure to conform to the thin ideal.
  • The politics of breathing: a cultural analysis of asthma in Australia.

1997

  • Psychological stress in the etiology of disordered eating.
  • Availability of health services for women in New South Wales.
  • The effectiveness of legal protection in the prevention of violence by partners in the lives of young Australian women.  
  • Road safety research project: Female drivers.
  • An examination of the factors relating to social isolation in the elderly.
  • Contraception and young women.
  • Older Australian women as widows.
  • Restraint, emotions and health in relation to binge eating.

1996

  • Women’s experiences of seeking help for emotional distress.
  • Life changes after the birth of a first child and usefulness of health care.
  • Analyse