Published Papers - Abstract 633

Alhazmi A, Stojanovski E, McEvoy M & Garg Manohar. Macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Results from the Australian Longitudinal Study on Women's Health. Public Health Nutrition Journal., 2014; 177: 1587-94

Objective: To investigate the association between macronutrient intake and type 2 diabetes risk in middle-aged Australian women.Design: A prospective cohort study, with 6 years (2002-2007) of follow up. Dietary intake was assessed with a validated FFQ. Relative risks with 95 % confidence intervals were used to examine risk associations.Setting: Australian Longitudinal Study on Women's Health, Australia.Subjects: Australian women (n 8370) from the Australian Longitudinal Study on Women's Health aged 45-50 years and free of type 2 diabetes at baseline.Results: After 6 years of follow-up, 311 women developed type 2 diabetes. After adjusting for sociodemographic, lifestyle and other dietary risk factors, MUFA, total n-3 PUFA, a-linolenic acid and total n-6 PUFA intakes were positively associated with the incidence of type 2 diabetes. The relative risks for type 2 diabetes for the highest compared with the lowest quintiles were 1.64 (95 % CI 1.06, 2.54), P = 0.04 for MUFA; 1.55 (95 % CI 1.03, 2.32), P = 0.01 for n-3 PUFA; 1.84 (95 % CI 1.25, 2.71), P < 0.01 for a-linolenic acid; and 1.60 (95 % CI 1.03, 2.48), P = 0.04 for n-6 PUFA. Other dietary macronutrients were not significantly associated with diabetes risk.Conclusions: The data indicate that consumption of MUFA, n-3 PUFA and n-6 PUFA may influence the risk of developing type 2 diabetes in women.

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