Published Papers - Abstract 855

Wilson L, Pandeya N, Byles J & Mishra G. Hot flushes and night sweats symptom profiles over a 17-year period in mid-aged women: The role of hysterectomy with ovarian conservation. Maturitas, 2016; 91: 2020-7-1 0

Objectives: There is limited research on hot flushes and night sweats in women with a hysterectomy withovarian conservation. We aimed to describe the patterns of these symptoms in a cohort of Australianwomen and to investigate the relationship between distinct symptom patterns and hysterectomy status.Study design and outcome measures: Repeated-measures latent class analysis (LCA) was used to identifyhot flushes and night sweats symptom patterns across seven surveys (over 17 years) in the mid-cohort ofthe Australian Longitudinal Study on Women’s Health. Multinomial logistic regression was used to assessthe associations of the symptom patterns in women with a hysterectomy with ovarian conservation(n = 1129) versus women without a hysterectomy (n = 4977).Results: A higher proportion of women with a hysterectomy than of those without experienced a constantpattern of hot flushes (15% versus 30%) and night sweats (9% versus 19%). Women with a hysterectomyhad higher odds of constant hot flushes versus minimal hot flushes (OR = 1.97, 95% CI: 1.64, 2.35) andconstant versus minimal night sweats (OR = 2.09, 95% CI: 1.70, 2.55). Smoking, a ‘lower level of educationto non-professional occupation’ pathway and body mass index (BMI) patterns of ‘always obese’ and‘increasingly obese’ were also associated with a higher risk of constant symptoms.Conclusions: Women who have a hysterectomy (with ovarian conservation) have a higher risk of hotflushes and night sweats that persist over an extended period.

Open Access Article