Title, Synopsis and Publications Investigators and Collaborators
Dietary zinc intake, incident type-2 diabetes and depression in Australian women
The primary aim of this project was to analyse measures of dietary zinc intake and dietary zinc to iron ratio in a random community based sample of women aged 45 to 50 years and determine if low zinc intake is associated with self-report incident type-2 diabetes and incident CESD depression. The project analysis and results for the type-2 diabetes componet of the project are complete. A total of 333 incident cases of diabetes were identified over 6 years of follow-up. After adjustment for dietary and non-dietary factors, the highest quintile of dietary zinc intake had almost half the odds of developing type-2 diabetes (OR=0.55, 95% C.I. 0.36 – 0.86) compared with the lowest quintile. Similar findings were observed for the zinc/iron ratio; the highest quintile had half the odds of developing T2D (OR=0.49, 95% C.I 0.29-0.80) after multivariate adjustment of covariates. A manuscript has been prepared and is currently under review in Diabetiologia. The analysis for the depression component of the project is ongoing and this will be written as a manuscript that will be submitted to the Journal of Affective disorders.
Publications: 740  658  
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Prof Julie Byles
A/Prof Mark McEvoy
Dr Zumin Shi
Dr Milton Hasnat
Professor David Sibbritt
Dr Amanda Patterson
Prof John Attia
Dr Patrick McElduff
Prof Deborah Loxton
Dr Khanrin Vashum
Dr Rafiqul Islam
Dr Alexis Hure