Details of Publication 402 for Project A224:

Herbert D, Lucke J & Dobson A. Infertility, medical advice and treatment with fertility hormones and/or in vitro fertilisation: A population perspective from the Australian Longitudinal Study on Women's Health. Australian and New Zealand Journal of Public Health, 2009; 33(4): 358-364

Objective: To identify the factors associated with infertility, seeking advice and treatment with fertility hormones and/or in vitro fertilisation (IVF) among a general population of women.Methods: Participants in the Australian Longitudinal Study on Women’s Health aged 28-33 years in 2006 had completed up to four mailed surveys over 10 years (n=9,145). Parsimonious multivariate logistic regression was used to identify the socio-demographic, biological (including reproductive histories), and behaviouralfactors associated with infertility, advice and hormonal/IVF treatment.Results: For women who had tried to conceive or had been pregnant (n=5,936), 17% reported infertility. Among women with infertility (n=1031), 72% (n=728) sought advice but only 50% (n=356) used hormonal/IVF treatment. Women had higher odds of infertility when: they had never been pregnant (OR=7.2, 95% CI 5.6-9.1) or had a history of miscarriage (OR range=1.5-4.0) than those who had given birth (and never had a miscarriage or termination).Conclusion: Only one-third of women with infertility used hormonal and/or IVF treatment. Women with PCOS or endometriosis were the most proactive in having sought advice and used hormonal/IVF treatment. Implications: Raised awareness of age-related declining fertility is important for partnered women aged ~30 years toencourage pregnancy during their prime reproductive years and reduce the risk of infertility.