Details of Publication 597 for Project A408:

Pavey T, Peeters G & Brown W. Sitting-time and 9-year all-cause mortality in older women. British Journal of Sports Medicine., 2015; 49(2): 95-99

Background: Studies of mid-aged adults provide evidence of a relationship between sitting-time and all-cause mortality, but evidence in older adults is limited. The aim is to examine the relationship between total sitting-time and all-cause mortality in older women.Methods: The prospective cohort design involved 6656 participants in the Australian Longitudinal Study on Women’s Health who were followed for up to 9 years (2002, age 76-81, to 2011, age 85-90). Self-reported total sitting-time was linked to all-cause mortality data from the National Death Index from 2002 to 2011. Cox proportional hazard models were used to examine the relationship between sitting-time and all-cause mortality, with adjustment for potential socio-demographic, behavioural and health confounders. Results: There were 2003 (30.1%) deaths during a median follow-up of 6-years. Compared with participants who sat <4 h/d, those who sat 8-11 h/d had a 1.45 times higher risk of death and those who sat =11 h/d had a 1.65 times higher risk of death. These risks remained after adding socio-demographic and behavioural covariates, but were attenuated after adjustment for health covariates.. A significant interaction (p=0.02) was found between sitting-time and physical activity (PA), with increased mortality risk for prolonged sitting only among participants not meeting PA guidelines (HR for sitting =8 h/d: 1.31, 95% CI 1.07-1.61); HR for sitting =11 h/d: 1.47, CI 1.15-1.93).Conclusions: Prolonged sitting-time was positively associated with all-cause mortality. Women who reported sitting for more than 8 h/d and did not meet physical activity guidelines had an increased risk of dying within the next 9 years.Pavey TG, Peeters GMEE, Brown WJ. (2015). Sitting time and 9 year all-cause mortality in older women. British Journal of Sports Medicine, 49(2), 95-9. doi: 10.1136/bjsports-2012-091676. Epub 2012 Dec 15.

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