Details of Publication 742 for Project A424:

Heesch K, Gellecum Y, Burton N, van Uffelen J & Brown W. Relationships between physical activity, walking and health-related quality of life in women with depressive symptoms. , 2014; : 158

Introduction: Physical activity (PA) can improve health-related quality of life (HRQL), particularly among those with poor physical health. The association between PA and HRQL in those with poor mental health is less clear. The aims of this study were to examine the concurrent and 9-year prospective dose-response relationships between each of total PA (TPA) and walking with HRQL in women with depressive symptoms. Methods: Participants were women born in 1946-1951, who completed mailed surveys for the Australian Longitudinal Study on Women's Health in 2001, 2004, 2007 and 2010, and who, in 2001, scored >10 points on the Center for Epidemiology Studies Depression questionnaire (N=1904). At each time point, women reported their weekly minutes of walking, moderate PA, and vigorous PA using the Active Australia Survey. A summary TPA score was created that took into account the differences in energy expenditure among the three PA types. TPA and walking were categorised into four levels (none, low, intermediate, sufficient). HRQL was measured with the Medical Outcomes Study Short-Form 36 Health Status Survey (SF-36). Multivariable mixed models, adjusted for socio-demographic and health-related variables, were used to examine associations between TPA level and SF-36 scores, including component summary scores and eight subscale scores. The same modelling approach was used to examine associations between walking and SF-36 scores for women who reported walking as their only PA. Results: Linear trends were observed between TPA and walking with SF-36 scores. Concurrently, higher levels of TPA and walking were associated with higher SF36 scores (p<0.05). The strongest associations (> 6-point differences) were found for physical functioning, vitality, and social functioning. In prospective models, associations were attenuated, more so for physical health SF-36 scores than social/emotional health SF-36 scores. Compared with women doing no TPA or walking, women doing “sufficient” TPA or walking had significantly higher scores for most SF-36 scales, and women doing an “intermediate” level of TPA or walking had higher scores for some SF-36 scales. Few prospective associations, however, were meaningful (=3 point differences).