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Progression of chronic diseases and conditions in mid-aged women and beyond: the role of reproductive health over the life course and medication use.

Synopsis

Multi-morbidity is a growing issue and poses a major challenge to health care systems around the world1,2. A number of gaps in multi-morbidity research need to be addressed. This study aims to investigate the progression of chronic diseases and conditions in mid-aged women and beyond from the ALSWH (1946-51) cohort. We aim to identify factors that are associated with disease progression and outcomes. We are particularly interested in how reproductive variables (e.g. age at menarche/menopause and number of children) influence the progression and outcomes as well as medication use and cost in this progression.