Australian Longitudinal Study on Women's Health
Search Icon Created with Sketch.
Icons / Login Created with Sketch.
Icons / User Created with Sketch.
Search Icon Created with Sketch.

Dietary inorganic nitrite/nitrite intake in a representative sample of Australian women, and cardiovascular disease risk.

Approved: 2017

Collaborators:

  • A/Prof Mark McEvoy
  • AProf Amanda Patterson
  • Dr Lesley MacDonald-Wicks
  • Ms Peta Forder
  • Mr Carl Holder
  • Dr Christopher Oldmeadow
  • Ms Jacklyn Jackson
  • Dr Natalie Ward
  • Dr Catherine Bondonno
  • Prof Jonathan Hodgson
  • Ms Lauren Blekkenhorst

Synopsis

Nitric Oxide (NO) is an important signalling molecule in the cardiovascular system and is vital for vascular function. Further, conditions of NO deficiency due to aging, diabetes and smoking are associated with the development of hypertension and atherosclerosis. Vegetables (especially beetroot and leafy greens) provide the richest dietary source of inorganic nitrate. Dietary nitrate can be utilized via the Nitrate-Nitrite-NO pathway to produce NO, indicating a relatively simple and cost effective method for restoring NO status.