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Life course weight trajectory and risk of type 2 diabetes


This project will use a life-course approach to examine the associations between weight trajectory patterns and subsequent risk of type 2 diabetes. In addition to examining the overall impacts of distinct weight trajectory patterns on type 2 diabetes risk, we will further explore impacts of various body mass index (BMI) metrics over the life course for those women who became obese after baseline, such as age at onset of obesity, duration of being obese, and obese-years (product of the degree and the duration of obesity similar conceptually to pack-years for smoking), on the risk of type 2 diabetes.