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Are calcium channel blockers associated with breast cancer? Assessing the impact of long-term use in large longitudinal cohorts

Synopsis

Breast cancer is the commonest cancer in women. Calcium channel blockers (CCBs) are frequently used worldwide to treat high blood pressure. A link between use of CCBs and breast cancer has been proposed with mixed findings in North American, European and Asian women. No data exist for Australian women. Since 1 in 8 Australian women will be diagnosed with breast cancer by age 85 years, it is important to determine whether this risk is increased by the use of CCBs.