W103: M-PreM study: Reproductive factors, from menarche to premenopause, and the risk of cardiometabolic and respiratory conditions before menopause.

M-PreM study: Reproductive factors, from menarche to premenopause, and the risk of cardiometabolic and respiratory conditions before menopause.

Approved: 2018

Collaborators:

Prof Gita Mishra
Prof Annette Dobson
Prof Deborah Loxton
Prof Helena Teede
Dr Anju Joham
Prof Rachel Huxley
Prof Debra Anderson
Dr Hsiu-Wen Chan
Dr Hsin-Fang Chung
Dr Charrlotte Seib
Prof Isabel Ferreira
Prof Grant Montgomery
Prof Jenny Doust
Prof Shyamali Dharmage
A/Prof Jenny Visser
Prof Harold (David) McIntyre
Prof Emmanuel Stamatakis
Prof Bu Yeap
Prof David Handelsman
Prof Alan Hayes
Dr Matthew Ahmadi
Mrs Leticia Watanabe Ribeiro
Dr Gregore Mielke
Mr Le Wei
Ms Chuyao Jin

Synopsis

Chronic conditions and poor health show marked sex differences in their prevalence and severity across the life course. Previous studies have typically focussed on risk factors for these conditions among postmenopausal women. This study maps the pathways between female reproductive factors, from the first period through to pregnancy and subfertility, and the risks of cardiometabolic and respiratory conditions and poor health among women in their 40s. This study involves conducting a range of biomedical tests (body size measurements, cognitive test, handgrip strength, lung function), fitting a physical activity monitor, and collecting blood samples to measure cardiometabolic and hormone markers and for biobanking.