Published Papers - Abstract 373

Helman J, Loxton D, Adamson L, Graves A & Powers J. Conducting substudies in a longitudinal research project. International Journal of Multiple Research Approaches, 2007; 1(2): 187-198

Longitudinal studies often include substudies which involve collection of specific and more detailed data from subsets of study participants. The longitudinal study framework adds methodological strength to these substudies through enabling sampling of individuals with exposures or outcomes of interest, and through retrospective and prospective access to longitudinal data. However, while there are many advantages to these studies, there are also a number of potential disadvantages. Here we describe some of the considerations when designing and approving a substudy and some of the procedures to be applied to ensure that the substudy runs well and has minimal impact on study participants.