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How does weight gain affect the probability of pregnancy and risk of key metabolic outcomes in women with PCOS?

Synopsis

Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders affecting 8 to 13 % of premenopausal women globally, making it a key public health burden. Once diagnosed, education, multidisciplinary care and lifestyle interventions for prevention or management of excess weight are important.

The aim of this study is to explore the impact of PCOS status and BMI change over time on different pregnancy outcomes and metabolic outcomes.