Details of Publication 467 for Project A258:

Berecki-Gisolf, J., McKenzie, S.J., Dobson, A.J., McFarlane, A., McLaughlin, D. A history of comorbid depression and anxiety predicts new onset of heart disease. Journal of Behavioral Medicine, 2013; 36(4): 347-353

The objective of the current study was to examine whether a history of comorbid depression and anxiety predicted new onset of heart disease. Data from 6 surveys, spanning 15 years, of the Australian Longitudinal Study on Women’s Health, a large prospective cohort study were used, including health status, lifestyle, and sociodemographic measures. Participants of the 1946–1951 cohort who did not self-report heart disease at surveys 1 (1996) and 2 (1998) were included in the study (n = 11,828). After adjusting for health status, lifestyle and sociodemographic factors, a history of comorbid depression and anxiety (odds ratio (OR) = 1.78; 95 % confidence interval (CI) = 1.41–2.24) was associated with new onset of heart disease. A history of comorbid depression and anxiety is an important predictor of new onset of heart disease in midaged women. Due to the possible detrimental consequences of heart disease, psychological factors as well as established predictors should be considered when assessing a person’s risk for heart disease.

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